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Structural Remodeling of the Human Colonic Mesenchyme in Inflammatory Bowel Disease
Intestinal mesenchymal cells play essential roles in epithelial homeostasis, matrix remodeling, immunity, and inflammation. But the extent of heterogeneity within the colonic mesenchyme in these processes remains unknown. Using unbiased single-cell profiling of over 16,500 colonic mesenchymal cells,...
Autores principales: | Kinchen, James, Chen, Hannah H., Parikh, Kaushal, Antanaviciute, Agne, Jagielowicz, Marta, Fawkner-Corbett, David, Ashley, Neil, Cubitt, Laura, Mellado-Gomez, Esther, Attar, Moustafa, Sharma, Eshita, Wills, Quin, Bowden, Rory, Richter, Felix C., Ahern, David, Puri, Kamal D., Henault, Jill, Gervais, Francois, Koohy, Hashem, Simmons, Alison |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176871/ https://www.ncbi.nlm.nih.gov/pubmed/30270042 http://dx.doi.org/10.1016/j.cell.2018.08.067 |
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