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Geometrical confinement controls the asymmetric patterning of brachyury in cultures of pluripotent cells

Diffusible signals are known to orchestrate patterning during embryogenesis, yet diffusion is sensitive to noise. The fact that embryogenesis is remarkably robust suggests that additional layers of regulation reinforce patterning. Here, we demonstrate that geometrical confinement orchestrates the sp...

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Detalles Bibliográficos
Autores principales: Blin, Guillaume, Wisniewski, Darren, Picart, Catherine, Thery, Manuel, Puceat, Michel, Lowell, Sally
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176930/
https://www.ncbi.nlm.nih.gov/pubmed/30115626
http://dx.doi.org/10.1242/dev.166025