Cargando…
Geometrical confinement controls the asymmetric patterning of brachyury in cultures of pluripotent cells
Diffusible signals are known to orchestrate patterning during embryogenesis, yet diffusion is sensitive to noise. The fact that embryogenesis is remarkably robust suggests that additional layers of regulation reinforce patterning. Here, we demonstrate that geometrical confinement orchestrates the sp...
Autores principales: | Blin, Guillaume, Wisniewski, Darren, Picart, Catherine, Thery, Manuel, Puceat, Michel, Lowell, Sally |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176930/ https://www.ncbi.nlm.nih.gov/pubmed/30115626 http://dx.doi.org/10.1242/dev.166025 |
Ejemplares similares
-
SyNPL: Synthetic Notch pluripotent cell lines to monitor and manipulate cell interactions in vitro and in vivo
por: Malaguti, Mattias, et al.
Publicado: (2022) -
The transcription factor E2A drives neural differentiation in pluripotent cells
por: Rao, Chandrika, et al.
Publicado: (2020) -
Brachyury and SMAD signalling collaboratively orchestrate distinct mesoderm and endoderm gene regulatory networks in differentiating human embryonic stem cells
por: Faial, Tiago, et al.
Publicado: (2015) -
Distinct Wnt-driven primitive streak-like populations reflect in vivo lineage precursors
por: Tsakiridis, Anestis, et al.
Publicado: (2014) -
N-cadherin stabilises neural identity by dampening anti-neural signals
por: Punovuori, Karolina, et al.
Publicado: (2019)