A nonalcoholic fatty liver disease model in human induced pluripotent stem cell-derived hepatocytes, created by endoplasmic reticulum stress-induced steatosis

Hepatic steatosis, a reversible state of metabolic dysregulation, can promote the onset of nonalcoholic steatohepatitis (NASH), and its transition is thought to be critical in disease evolution. The association between endoplasmic reticulum (ER) stress response and hepatocyte metabolism disorders pr...

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Detalles Bibliográficos
Autores principales: Parafati, Maddalena, Kirby, R. Jason, Khorasanizadeh, Sepideh, Rastinejad, Fraydoon, Malany, Siobhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176998/
https://www.ncbi.nlm.nih.gov/pubmed/30254132
http://dx.doi.org/10.1242/dmm.033530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176998/
https://www.ncbi.nlm.nih.gov/pubmed/30254132
http://dx.doi.org/10.1242/dmm.033530

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