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Effects of genetic deletion versus pharmacological blockade of the LPA(1) receptor on depression-like behaviour and related brain functional activity

Animal models of psychopathology are particularly useful for studying the neurobiology of depression and characterising the subtypes. Recently, our group was the first to identify a possible relationship between the LPA(1) receptor and a mixed anxiety-depression phenotype. Specifically, maLPA(1)-nul...

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Detalles Bibliográficos
Autores principales: Moreno-Fernández, Román Darío, Nieto-Quero, Andrea, Gómez-Salas, Francisco Javier, Chun, Jerold, Estivill-Torrús, Guillermo, Rodríguez de Fonseca, Fernando, Santín, Luis Javier, Pérez-Martín, Margarita, Pedraza, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177006/
https://www.ncbi.nlm.nih.gov/pubmed/30061118
http://dx.doi.org/10.1242/dmm.035519