Intrinsic activation of the vitamin D antimicrobial pathway by M. leprae infection is inhibited by type I IFN

Following infection, virulent mycobacteria persist and grow within the macrophage, suggesting that the intrinsic activation of an innate antimicrobial response is subverted by the intracellular pathogen. For Mycobacterium leprae, the intracellular bacterium that causes leprosy, the addition of exoge...

Descripción completa

Detalles Bibliográficos
Autores principales: Zavala, Kathryn, Gottlieb, Carter A., Teles, Rosane M., Adams, John S., Hewison, Martin, Modlin, Robert L., Liu, Philip T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177120/
https://www.ncbi.nlm.nih.gov/pubmed/30300363
http://dx.doi.org/10.1371/journal.pntd.0006815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177120/
https://www.ncbi.nlm.nih.gov/pubmed/30300363
http://dx.doi.org/10.1371/journal.pntd.0006815

Ejemplares similares