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Intrinsic activation of the vitamin D antimicrobial pathway by M. leprae infection is inhibited by type I IFN
Following infection, virulent mycobacteria persist and grow within the macrophage, suggesting that the intrinsic activation of an innate antimicrobial response is subverted by the intracellular pathogen. For Mycobacterium leprae, the intracellular bacterium that causes leprosy, the addition of exoge...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177120/ https://www.ncbi.nlm.nih.gov/pubmed/30300363 http://dx.doi.org/10.1371/journal.pntd.0006815 |