A type 2 diabetes disease module with a high collective influence for Cdk2 and PTPLAD1 is localized in endosomes

Despite the identification of many susceptibility genes our knowledge of the underlying mechanisms responsible for complex disease remains limited. Here, we identified a type 2 diabetes disease module in endosomes, and validate it for functional relevance on selected nodes. Using hepatic Golgi/endos...

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Detalles Bibliográficos
Autores principales: Boutchueng-Djidjou, Martial, Belleau, Pascal, Bilodeau, Nicolas, Fortier, Suzanne, Bourassa, Sylvie, Droit, Arnaud, Elowe, Sabine, Faure, Robert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177195/
https://www.ncbi.nlm.nih.gov/pubmed/30300385
http://dx.doi.org/10.1371/journal.pone.0205180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177195/
https://www.ncbi.nlm.nih.gov/pubmed/30300385
http://dx.doi.org/10.1371/journal.pone.0205180

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