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A type 2 diabetes disease module with a high collective influence for Cdk2 and PTPLAD1 is localized in endosomes
Despite the identification of many susceptibility genes our knowledge of the underlying mechanisms responsible for complex disease remains limited. Here, we identified a type 2 diabetes disease module in endosomes, and validate it for functional relevance on selected nodes. Using hepatic Golgi/endos...
Autores principales: | Boutchueng-Djidjou, Martial, Belleau, Pascal, Bilodeau, Nicolas, Fortier, Suzanne, Bourassa, Sylvie, Droit, Arnaud, Elowe, Sabine, Faure, Robert L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177195/ https://www.ncbi.nlm.nih.gov/pubmed/30300385 http://dx.doi.org/10.1371/journal.pone.0205180 |
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