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Evolutionary footprint of epistasis

Variation of an inherited trait across a population cannot be explained by additive contributions of relevant genes, due to epigenetic effects and biochemical interactions (epistasis). Detecting epistasis in genomic data still represents a significant challenge that requires a better understanding o...

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Detalles Bibliográficos
Autores principales: Pedruzzi, Gabriele, Barlukova, Ayuna, Rouzine, Igor M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177197/
https://www.ncbi.nlm.nih.gov/pubmed/30222748
http://dx.doi.org/10.1371/journal.pcbi.1006426