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Neuroprotective effects of TRPA1 channels in the cerebral endothelium following ischemic stroke

Hypoxia and ischemia are linked to oxidative stress, which can activate the oxidant-sensitive transient receptor potential ankyrin 1 (TRPA1) channel in cerebral artery endothelial cells, leading to vasodilation. We hypothesized that TRPA1 channels in endothelial cells are activated by hypoxia-derive...

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Detalles Bibliográficos
Autores principales: Pires, Paulo Wagner, Earley, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177258/
https://www.ncbi.nlm.nih.gov/pubmed/30239332
http://dx.doi.org/10.7554/eLife.35316