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Ancient mechanisms for the evolution of the bicoid homeodomain's function in fly development

The ancient mechanisms that caused developmental gene regulatory networks to diversify among distantly related taxa are not well understood. Here we use ancestral protein reconstruction, biochemical experiments, and developmental assays of transgenic animals carrying reconstructed ancestral genes to...

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Detalles Bibliográficos
Autores principales: Liu, Qinwen, Onal, Pinar, Datta, Rhea R, Rogers, Julia M, Schmidt-Ott, Urs, Bulyk, Martha L, Small, Stephen, Thornton, Joseph W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177261/
https://www.ncbi.nlm.nih.gov/pubmed/30298815
http://dx.doi.org/10.7554/eLife.34594