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Background selection and biased gene conversion affect more than 95% of the human genome and bias demographic inferences

Disentangling the effect on genomic diversity of natural selection from that of demography is notoriously difficult, but necessary to properly reconstruct the history of species. Here, we use high-quality human genomic data to show that purifying selection at linked sites (i.e. background selection,...

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Detalles Bibliográficos
Autores principales: Pouyet, Fanny, Aeschbacher, Simon, Thiéry, Alexandre, Excoffier, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177262/
https://www.ncbi.nlm.nih.gov/pubmed/30125248
http://dx.doi.org/10.7554/eLife.36317