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Background selection and biased gene conversion affect more than 95% of the human genome and bias demographic inferences
Disentangling the effect on genomic diversity of natural selection from that of demography is notoriously difficult, but necessary to properly reconstruct the history of species. Here, we use high-quality human genomic data to show that purifying selection at linked sites (i.e. background selection,...
Autores principales: | Pouyet, Fanny, Aeschbacher, Simon, Thiéry, Alexandre, Excoffier, Laurent |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177262/ https://www.ncbi.nlm.nih.gov/pubmed/30125248 http://dx.doi.org/10.7554/eLife.36317 |
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