Liposomal codelivery of an SN38 prodrug and a survivin siRNA for tumor therapy

PURPOSE: A liposome-based siRNA–drug combination was evaluated as a potential therapeutic strategy to improve the curative effect. METHODS: A topoisomerase inhibitor SN38 prodrug was combined with a survivin siRNA through codelivery using transferrin (Tf)-L-SN38/P/siRNA. In this combination, SN38 wa...

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Detalles Bibliográficos
Autores principales: Bi, Ye, Lee, Robert J, Wang, Xinyu, Sun, Yating, Wang, Mengqiao, Li, Lianlian, Li, Chenliang, Xie, Jing, Teng, Lesheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177376/
https://www.ncbi.nlm.nih.gov/pubmed/30323583
http://dx.doi.org/10.2147/IJN.S173279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177376/
https://www.ncbi.nlm.nih.gov/pubmed/30323583
http://dx.doi.org/10.2147/IJN.S173279

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