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Replacing the Draize eye test: Impedance spectroscopy as a 3R method to discriminate between all GHS categories for eye irritation

Highly invasive animal based test procedures for risk assessment such as the Draize eye test are under increasing criticism due to poor transferability for the human organism and animal-welfare concerns. However, besides all efforts, the Draize eye test is still not completely replaced by alternativ...

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Detalles Bibliográficos
Autores principales: Lotz, C., Kiesewetter, L., Schmid, F. F., Hansmann, J., Walles, H., Groeber-Becker, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177390/
https://www.ncbi.nlm.nih.gov/pubmed/30301970
http://dx.doi.org/10.1038/s41598-018-33118-2