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Replacing the Draize eye test: Impedance spectroscopy as a 3R method to discriminate between all GHS categories for eye irritation
Highly invasive animal based test procedures for risk assessment such as the Draize eye test are under increasing criticism due to poor transferability for the human organism and animal-welfare concerns. However, besides all efforts, the Draize eye test is still not completely replaced by alternativ...
Autores principales: | Lotz, C., Kiesewetter, L., Schmid, F. F., Hansmann, J., Walles, H., Groeber-Becker, F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177390/ https://www.ncbi.nlm.nih.gov/pubmed/30301970 http://dx.doi.org/10.1038/s41598-018-33118-2 |
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