Overlapping motifs on the herpes viral proteins ICP27 and ORF57 mediate interactions with the mRNA export adaptors ALYREF and UIF

The TREX complex mediates the passage of bulk cellular mRNA export to the nuclear export factor TAP/NXF1 via the export adaptors ALYREF or UIF, which appear to act in a redundant manner. TREX complex recruitment to nascent RNA is coupled with 5′ capping, splicing and polyadenylation. Therefore to fa...

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Detalles Bibliográficos
Autores principales: Tunnicliffe, Richard B., Tian, Xiaochen, Storer, Joanna, Sandri-Goldin, Rozanne M., Golovanov, Alexander P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177440/
https://www.ncbi.nlm.nih.gov/pubmed/30301920
http://dx.doi.org/10.1038/s41598-018-33379-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177440/
https://www.ncbi.nlm.nih.gov/pubmed/30301920
http://dx.doi.org/10.1038/s41598-018-33379-x

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