Naturally Occurring Variations Modulate the Activity of the HPV33 Early Promoter and its Affinity for the E2 Transcription Factor

The human papillomavirus (HPV) Long Control Region (LCR) encompasses the early promoter (EP) that drives transcription of the E6 and E7 oncogenes in keratinocytes and HPV-associated cancers. In this study, the transcriptional activities of the HPV33 EP from the prototype LCR and from eight variants...

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Detalles Bibliográficos
Autores principales: Alvarez, Jennifer, Gagnon, David, Coutlée, François, Archambault, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177462/
https://www.ncbi.nlm.nih.gov/pubmed/30301935
http://dx.doi.org/10.1038/s41598-018-33243-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177462/
https://www.ncbi.nlm.nih.gov/pubmed/30301935
http://dx.doi.org/10.1038/s41598-018-33243-y

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