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The aged rhesus macaque manifests Braak stage III/IV Alzheimer’s-like pathology

INTRODUCTION: An animal model of late-onset Alzheimer’s disease is needed to research what causes degeneration in the absence of dominant genetic insults and why the association cortex is particularly vulnerable to degeneration. METHODS: We studied the progression of tau and amyloid cortical patholo...

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Detalles Bibliográficos
Autores principales: Paspalas, Constantinos D., Carlyle, Becky C., Leslie, Shannon, Preuss, Todd M., Crimins, Johanna L., Huttner, Anita J., van Dyck, Christopher H., Rosene, Douglas L., Nairn, Angus C., Arnsten, Amy F. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178089/
https://www.ncbi.nlm.nih.gov/pubmed/29241829
http://dx.doi.org/10.1016/j.jalz.2017.11.005