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Epithelial Cells Attenuate Toll-Like Receptor-Mediated Inflammatory Responses in Monocyte-Derived Macrophage-Like Cells to Mycobacterium tuberculosis by Modulating the PI3K/Akt/mTOR Signaling Pathway

Both alveolar macrophages (AMs) and alveolar epithelial cells (AECs) are main targets of Mycobacterium tuberculosis (M. tuberculosis (Mtb)). Intercellular communications between mucosal AECs and AMs have important implications in cellular responses to exogenous insults. However, molecular mechanisms...

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Detalles Bibliográficos
Autores principales: Yang, Yi, Sun, Yingfei, Xu, Jinrui, Bao, Kangda, Luo, Meihui, Liu, Xiaoming, Wang, Yujiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178170/
https://www.ncbi.nlm.nih.gov/pubmed/30356420
http://dx.doi.org/10.1155/2018/3685948