Inactivation of PLK4-STIL Module Prevents Self-Renewal and Triggers p53-Dependent Differentiation in Human Pluripotent Stem Cells

Centrioles account for centrosomes and cilia formation. Recently, a link between centrosomal components and human developmental disorders has been established. However, the exact mechanisms how centrosome abnormalities influence embryogenesis and cell fate are not understood. PLK4-STIL module repres...

Descripción completa

Detalles Bibliográficos
Autores principales: Renzova, Tereza, Bohaciakova, Dasa, Esner, Milan, Pospisilova, Veronika, Barta, Tomas, Hampl, Ales, Cajanek, Lukas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178195/
https://www.ncbi.nlm.nih.gov/pubmed/30197118
http://dx.doi.org/10.1016/j.stemcr.2018.08.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178195/
https://www.ncbi.nlm.nih.gov/pubmed/30197118
http://dx.doi.org/10.1016/j.stemcr.2018.08.008

Ejemplares similares