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Inactivation of PLK4-STIL Module Prevents Self-Renewal and Triggers p53-Dependent Differentiation in Human Pluripotent Stem Cells

Centrioles account for centrosomes and cilia formation. Recently, a link between centrosomal components and human developmental disorders has been established. However, the exact mechanisms how centrosome abnormalities influence embryogenesis and cell fate are not understood. PLK4-STIL module repres...

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Detalles Bibliográficos
Autores principales:	Renzova, Tereza, Bohaciakova, Dasa, Esner, Milan, Pospisilova, Veronika, Barta, Tomas, Hampl, Ales, Cajanek, Lukas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178195/ https://www.ncbi.nlm.nih.gov/pubmed/30197118 http://dx.doi.org/10.1016/j.stemcr.2018.08.008

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