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Rapid Mast Cell Generation from Gata2 Reporter Pluripotent Stem Cells

Mast cells are tissue-resident immune cells. Their overgrowth/overactivation results in a range of common distressing, sometimes life-threatening disorders, including asthma, psoriasis, anaphylaxis, and mastocytosis. Currently, drug discovery is hampered by use of cancer-derived mast cell lines or p...

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Detalles Bibliográficos
Autores principales: Kauts, Mari-Liis, De Leo, Bianca, Rodríguez-Seoane, Carmen, Ronn, Roger, Glykofrydis, Fokion, Maglitto, Antonio, Kaimakis, Polynikis, Basi, Margarita, Taylor, Helen, Forrester, Lesley, Wilkinson, Adam C., Göttgens, Berthold, Saunders, Philippa, Dzierzak, Elaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178197/
https://www.ncbi.nlm.nih.gov/pubmed/30197119
http://dx.doi.org/10.1016/j.stemcr.2018.08.007