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Rapid Mast Cell Generation from Gata2 Reporter Pluripotent Stem Cells
Mast cells are tissue-resident immune cells. Their overgrowth/overactivation results in a range of common distressing, sometimes life-threatening disorders, including asthma, psoriasis, anaphylaxis, and mastocytosis. Currently, drug discovery is hampered by use of cancer-derived mast cell lines or p...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178197/ https://www.ncbi.nlm.nih.gov/pubmed/30197119 http://dx.doi.org/10.1016/j.stemcr.2018.08.007 |