Cargando…
Rapid Mast Cell Generation from Gata2 Reporter Pluripotent Stem Cells
Mast cells are tissue-resident immune cells. Their overgrowth/overactivation results in a range of common distressing, sometimes life-threatening disorders, including asthma, psoriasis, anaphylaxis, and mastocytosis. Currently, drug discovery is hampered by use of cancer-derived mast cell lines or p...
Autores principales: | Kauts, Mari-Liis, De Leo, Bianca, Rodríguez-Seoane, Carmen, Ronn, Roger, Glykofrydis, Fokion, Maglitto, Antonio, Kaimakis, Polynikis, Basi, Margarita, Taylor, Helen, Forrester, Lesley, Wilkinson, Adam C., Göttgens, Berthold, Saunders, Philippa, Dzierzak, Elaine |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178197/ https://www.ncbi.nlm.nih.gov/pubmed/30197119 http://dx.doi.org/10.1016/j.stemcr.2018.08.007 |
Ejemplares similares
-
In Vitro Differentiation of Gata2 and Ly6a Reporter Embryonic Stem Cells Corresponds to In Vivo Waves of Hematopoietic Cell Generation
por: Kauts, Mari-Liis, et al.
Publicado: (2017) -
Gata2 is required for HSC generation and survival
por: de Pater, Emma, et al.
Publicado: (2013) -
In vivo single cell analysis reveals Gata2 dynamics in cells transitioning to hematopoietic fate
por: Eich, Christina, et al.
Publicado: (2018) -
Hematopoietic (stem) cell development — how divergent are the roads taken?
por: Kauts, Mari‐Liis, et al.
Publicado: (2016) -
Engineering pattern formation and morphogenesis
por: Davies, Jamie A., et al.
Publicado: (2020)