HIT-Cas9: A CRISPR/Cas9 Genome-Editing Device under Tight and Effective Drug Control

The CRISPR/Cas9 enabled efficient gene editing in an easy and programmable manner. Controlling its activity in greater precision is desired for biomedical research and potential therapeutic translation. Here, we engrafted the CRISPR/Cas9 system with a mutated human estrogen receptor (ER(T2)), which...

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Detalles Bibliográficos
Autores principales: Zhao, Chen, Zhao, Yingze, Zhang, Jingfang, Lu, Jia, Chen, Li, Zhang, Yue, Ying, Yue, Xu, Junjun, Wei, Shixian, Wang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178243/
https://www.ncbi.nlm.nih.gov/pubmed/30312845
http://dx.doi.org/10.1016/j.omtn.2018.08.022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178243/
https://www.ncbi.nlm.nih.gov/pubmed/30312845
http://dx.doi.org/10.1016/j.omtn.2018.08.022

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