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Neurophysiological signals as predictive translational biomarkers for Alzheimer’s disease treatment: effects of donepezil on neuronal network oscillations in TgF344-AD rats

BACKGROUND: Translational research in Alzheimer’s disease (AD) pathology provides evidence that accumulation of amyloid-β and hyperphosphorylated tau, neuropathological hallmarks of AD, is associated with complex disturbances in synaptic and neuronal function leading to oscillatory abnormalities in...

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Detalles Bibliográficos
Autores principales: Stoiljkovic, Milan, Kelley, Craig, Horvath, Tamas L., Hajós, Mihály
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178257/
https://www.ncbi.nlm.nih.gov/pubmed/30301466
http://dx.doi.org/10.1186/s13195-018-0433-4