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Comparative cell biological study of in vitro antitumor and antimetastatic activity on melanoma cells of GnRH-III-containing conjugates modified with short-chain fatty acids

Background: Peptide hormone-based targeted tumor therapy is an approved strategy to selectively block the tumor growth and spreading. The gonadotropin-releasing hormone receptors (GnRH-R) overexpressed on different tumors (e.g., melanoma) could be utilized for drug-targeting by application of a GnRH...

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Detalles Bibliográficos
Autores principales: Lajkó, Eszter, Spring, Sarah, Hegedüs, Rózsa, Biri-Kovács, Beáta, Ingebrandt, Sven, Mező, Gábor, Kőhidai, László
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178282/
https://www.ncbi.nlm.nih.gov/pubmed/30344773
http://dx.doi.org/10.3762/bjoc.14.226