Prior anti-CAFs break down the CAFs barrier and improve accumulation of docetaxel micelles in tumor

BACKGROUND: Abnormal expression of stromal cells and extracellular matrix in tumor stroma creates a tight barrier, leading to insufficient extravasation and penetration of therapeutic agents. Cancer-associated fibroblasts (CAFs) take on pivotal roles encouraging tumor progression. METHOD: To surmoun...

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Detalles Bibliográficos
Autores principales: Pang, Ning, Li, Ji, Sun, Aning, Yang, Zhenzhen, Cheng, Shixuan, Qi, Xian-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178342/
https://www.ncbi.nlm.nih.gov/pubmed/30323586
http://dx.doi.org/10.2147/IJN.S171224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178342/
https://www.ncbi.nlm.nih.gov/pubmed/30323586
http://dx.doi.org/10.2147/IJN.S171224

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