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Prior anti-CAFs break down the CAFs barrier and improve accumulation of docetaxel micelles in tumor

BACKGROUND: Abnormal expression of stromal cells and extracellular matrix in tumor stroma creates a tight barrier, leading to insufficient extravasation and penetration of therapeutic agents. Cancer-associated fibroblasts (CAFs) take on pivotal roles encouraging tumor progression. METHOD: To surmoun...

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Detalles Bibliográficos
Autores principales:	Pang, Ning, Li, Ji, Sun, Aning, Yang, Zhenzhen, Cheng, Shixuan, Qi, Xian-Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178342/ https://www.ncbi.nlm.nih.gov/pubmed/30323586 http://dx.doi.org/10.2147/IJN.S171224

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