Cargando…

Apelin inhibited epithelial−mesenchymal transition of podocytes in diabetic mice through downregulating immunoproteasome subunits β5i

The epithelial−mesenchymal transition (EMT) of podocytes had been reported to be involved in the glomerular fibrosis in diabetic kidney diseases, which was regulated by TGFβ and NFκB pathways. And apelin, an adipokine which is upregulated in diabetic kidney diseases, was reported to be negatively co...

Descripción completa

Detalles Bibliográficos
Autores principales: Yin, Jiming, Wang, Yangjia, Chang, Jing, Li, Bin, Zhang, Jia, Liu, Yu, Lai, Song, Jiang, Ying, Li, Huihua, Zeng, Xiangjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178343/
https://www.ncbi.nlm.nih.gov/pubmed/30301930
http://dx.doi.org/10.1038/s41419-018-1098-4