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Tracking Tumor Colonization in Xenograft Mouse Models Using Accelerator Mass Spectrometry

Here we introduce an Accelerator Mass Spectrometry (AMS)-based high precision method for quantifying the number of cancer cells that initiate metastatic tumors, in xenograft mice. Quantification of (14)C per cell prior to injection into animals, and quantification of (14)C in whole organs allows us...

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Detalles Bibliográficos
Autores principales: Hum, Nicholas R., Martin, Kelly A., Malfatti, Michael A., Haack, Kurt, Buchholz, Bruce A., Loots, Gabriela G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178347/
https://www.ncbi.nlm.nih.gov/pubmed/30302019
http://dx.doi.org/10.1038/s41598-018-33368-0