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Intranasal delivery of a Fas-blocking peptide attenuates Fas-mediated apoptosis in brain ischemia
Ischemic stroke-induced neuronal cell death results in the permanent disabling of brain function. Apoptotic mechanisms are thought to play a prominent role in neuronal injury and ample evidence implicates Fas signaling in mediating cell death. In this study, we describe the neuroprotective effects o...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178348/ https://www.ncbi.nlm.nih.gov/pubmed/30301943 http://dx.doi.org/10.1038/s41598-018-33296-z |