Metastatic adrenocortical carcinoma displays higher mutation rate and tumor heterogeneity than primary tumors

Adrenocortical cancer (ACC) is a rare cancer with poor prognosis and high mortality due to metastatic disease. All reported genetic alterations have been in primary ACC, and it is unknown if there is molecular heterogeneity in ACC. Here, we report the genetic changes associated with metastatic ACC c...

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Detalles Bibliográficos
Autores principales: Gara, Sudheer Kumar, Lack, Justin, Zhang, Lisa, Harris, Emerson, Cam, Margaret, Kebebew, Electron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178360/
https://www.ncbi.nlm.nih.gov/pubmed/30301885
http://dx.doi.org/10.1038/s41467-018-06366-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178360/
https://www.ncbi.nlm.nih.gov/pubmed/30301885
http://dx.doi.org/10.1038/s41467-018-06366-z

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