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Metastatic adrenocortical carcinoma displays higher mutation rate and tumor heterogeneity than primary tumors
Adrenocortical cancer (ACC) is a rare cancer with poor prognosis and high mortality due to metastatic disease. All reported genetic alterations have been in primary ACC, and it is unknown if there is molecular heterogeneity in ACC. Here, we report the genetic changes associated with metastatic ACC c...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178360/ https://www.ncbi.nlm.nih.gov/pubmed/30301885 http://dx.doi.org/10.1038/s41467-018-06366-z |