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Staufen1 Interacts with Multiple Components of the Ebola Virus Ribonucleoprotein and Enhances Viral RNA Synthesis

Ebola virus (EBOV) genome and mRNAs contain long, structured regions that could hijack host RNA-binding proteins to facilitate infection. We performed RNA affinity chromatography coupled with mass spectrometry to identify host proteins that bind to EBOV RNAs and identified four high-confidence provi...

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Detalles Bibliográficos
Autores principales: Fang, Jingru, Pietzsch, Colette, Ramanathan, Palaniappan, Santos, Rodrigo I., Ilinykh, Philipp A., Garcia-Blanco, Mariano A., Bukreyev, Alexander, Bradrick, Shelton S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178623/
https://www.ncbi.nlm.nih.gov/pubmed/30301857
http://dx.doi.org/10.1128/mBio.01771-18