Cargando…

Staufen1 Interacts with Multiple Components of the Ebola Virus Ribonucleoprotein and Enhances Viral RNA Synthesis

Ebola virus (EBOV) genome and mRNAs contain long, structured regions that could hijack host RNA-binding proteins to facilitate infection. We performed RNA affinity chromatography coupled with mass spectrometry to identify host proteins that bind to EBOV RNAs and identified four high-confidence provi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fang, Jingru, Pietzsch, Colette, Ramanathan, Palaniappan, Santos, Rodrigo I., Ilinykh, Philipp A., Garcia-Blanco, Mariano A., Bukreyev, Alexander, Bradrick, Shelton S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178623/ https://www.ncbi.nlm.nih.gov/pubmed/30301857 http://dx.doi.org/10.1128/mBio.01771-18

Ejemplares similares

Functional interactomes of the Ebola virus polymerase identified by proximity proteomics in the context of viral replication
por: Fang, Jingru, et al.
Publicado: (2022)

Molecular Composition of Staufen2-Containing Ribonucleoproteins in Embryonic Rat Brain
por: Maher-Laporte, Marjolaine, et al.
Publicado: (2010)

Ebola Virus NP Binding to Host Protein Phosphatase-1 Regulates Capsid Formation
por: Ahmad, Asrar, et al.
Publicado: (2023)

Blocking of ebolavirus spread through intercellular connections by an MPER-specific antibody depends on BST2/tetherin
por: Santos, Rodrigo I., et al.
Publicado: (2023)

Species-Specific Evolution of Ebola Virus during Replication in Human and Bat Cells
por: Whitfield, Zachary J., et al.
Publicado: (2020)

Ebola Virus Binding to Tim-1 on T Lymphocytes Induces a Cytokine Storm
por: Younan, Patrick, et al.
Publicado: (2017)

Antiviral protection by antibodies targeting the glycan cap of Ebola virus glycoprotein requires activation of the complement system
por: Bukreyev, Alexander, et al.
Publicado: (2023)

Identification of Proteins Bound to Dengue Viral RNA In Vivo Reveals New Host Proteins Important for Virus Replication
por: Phillips, Stacia L., et al.
Publicado: (2016)

Ebola virus-mediated T-lymphocyte depletion is the result of an abortive infection
por: Younan, Patrick, et al.
Publicado: (2019)

Ubiquitination of Ebola virus VP35 at lysine 309 regulates viral transcription and assembly
por: van Tol, Sarah, et al.
Publicado: (2022)

Topoisomerase III-β is required for efficient replication of positive-sense RNA viruses
por: Prasanth, K. Reddisiva, et al.
Publicado: (2020)

Topoisomerase III-ß is required for efficient replication of positive-sense RNA viruses
por: Prasanth, K. Reddisiva, et al.
Publicado: (2020)

Ebolavirus Species-Specific Interferon Antagonism Mediated by VP24
por: Ramanathan, Palaniappan, et al.
Publicado: (2023)

Antibody Repertoires to the Same Ebola Vaccine Antigen Are Differentially Affected by Vaccine Vectors
por: Meyer, Michelle, et al.
Publicado: (2018)

Staufen1 Protein Participates Positively in the Viral RNA Replication of Enterovirus 71
por: Chen, Young-Mao, et al.
Publicado: (2019)

Ebola VP40 in Exosomes Can Cause Immune Cell Dysfunction
por: Pleet, Michelle L., et al.
Publicado: (2016)

Characterization of Staufen1 Ribonucleoproteins by Mass Spectrometry and Biochemical Analyses Reveal the Presence of Diverse Host Proteins Associated with Human Immunodeficiency Virus Type 1
por: Milev, Miroslav P., et al.
Publicado: (2012)

Corrigendum: Ebola VP40 in Exosomes Can Cause Immune Cell Dysfunction
por: Pleet, Michelle L., et al.
Publicado: (2018)

Targeting the Non-catalytic RVxF Site of Protein Phosphatase-1 With Small Molecules for Ebola Virus Inhibition
por: Lin, Xionghao, et al.
Publicado: (2019)

A rapid and simple quantitative method for specific detection of smaller coterminal RNA by PCR (DeSCo-PCR): application to the detection of viral subgenomic RNAs
por: Kanodia, Pulkit, et al.
Publicado: (2020)

Components and Architecture of the Rhabdovirus Ribonucleoprotein Complex
por: Riedel, Christiane, et al.
Publicado: (2020)

Role of RNA-binding proteins during the late stages of Flavivirus replication cycle
por: Diosa-Toro, Mayra, et al.
Publicado: (2020)

BROADLY NEUTRALIZING ANTIBODIES FROM HUMAN SURVIVORS TARGET A CONSERVED SITE IN THE EBOLA VIRUS GLYCOPROTEIN HR2/MPER REGION
por: Flyak, Andrew I., et al.
Publicado: (2018)

Cytoplasmic Ribonucleoprotein Components of the Novikoff Hepatoma
por: Kuff, Edward L., et al.
Publicado: (1960)

HIV-1 requires Staufen1 to dissociate stress granules and to produce infectious viral particles
por: Rao, Shringar, et al.
Publicado: (2019)

What Do Antibody Studies Tell Us about Viral Infections?
por: Ilinykh, Philipp A., et al.
Publicado: (2022)

Topoisomerase II Inhibitors Induce DNA Damage-Dependent Interferon Responses Circumventing Ebola Virus Immune Evasion
por: Luthra, Priya, et al.
Publicado: (2017)

Antisense modulation of IL7R splicing to control sIL7R expression in human CD4(+) T cells
por: Galarza-Muñoz, Gaddiel, et al.
Publicado: (2022)

The Ebola Interferon Inhibiting Domains Attenuate and Dysregulate Cell-Mediated Immune Responses
por: Lubaki, Ndongala Michel, et al.
Publicado: (2016)

Encapsidation of Staufen-2 Enhances Infectivity of HIV-1
por: Balakrishnan, Kannan, et al.
Publicado: (2021)

Viral genomics in Ebola virus research
por: Di Paola, Nicholas, et al.
Publicado: (2020)

Dysregulation of H/ACA ribonucleoprotein components in chronic lymphocytic leukemia
por: Dos Santos, Patricia Carolina, et al.
Publicado: (2017)

Staufen1-mediated mRNA decay induces Requiem mRNA decay through binding of Staufen1 to the Requiem 3′UTR
por: Kim, Min Young, et al.
Publicado: (2014)

Disabling of lymphocyte immune response by Ebola virus
por: Younan, Patrick, et al.
Publicado: (2018)

G Protein-Coupled Receptor Kinase 2 Promotes Flaviviridae Entry and Replication
por: Le Sommer, Caroline, et al.
Publicado: (2012)

The 5′ and 3′ Untranslated Regions of the Flaviviral Genome
por: Ng, Wy Ching, et al.
Publicado: (2017)

Ribosomal stalk proteins RPLP1 and RPLP2 promote biogenesis of flaviviral and cellular multi-pass transmembrane proteins
por: Campos, Rafael K, et al.
Publicado: (2020)

Causes and Consequences of Flavivirus RNA Methylation
por: Bradrick, Shelton S.
Publicado: (2017)

The multifunctional Staufen proteins: conserved roles from neurogenesis to synaptic plasticity
por: Heraud-Farlow, Jacki E., et al.
Publicado: (2014)

The Toll-Like Receptor 4 Antagonist Eritoran Protects Mice from Lethal Filovirus Challenge
por: Younan, Patrick, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_colvihu6utvee4m1k1f5238teg