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Comparison of antithrombin‐dependent and direct inhibitors of factor Xa or thrombin on the kinetics and qualitative characteristics of blood clots

BACKGROUND: Venous thromboembolism (VTE) is associated with significant morbidity and mortality. OBJECTIVES: We investigated the impact of direct and AT‐dependent FXa or thrombin inhibitors on thrombus formation. METHODS: Whole blood thromboelastometry and thrombin generation were assessed after tri...

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Detalles Bibliográficos
Autores principales: Salta, Stella, Papageorgiou, Loula, Larsen, Annette K., Van Dreden, Patrick, Soulier, Claire, Cokkinos, Dennis V., Elalamy, Ismail, Gerotziafas, Grigoris T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178701/
https://www.ncbi.nlm.nih.gov/pubmed/30349889
http://dx.doi.org/10.1002/rth2.12120