Ethacrynic acid decreases expression of proinflammatory intestinal wall cytokines and ameliorates gastrointestinal stasis in murine postoperative ileus

OBJECTIVES: Several compounds characterized by an olefin linkage conjugated to a carbonyl group have anti-inflammatory properties. The diuretic ethacrynic acid (EA) is a compound of this type. Herein, we tested the hypothesis that ethacrynic acid can modulate the development of ileus after bowel man...

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Detalles Bibliográficos
Autores principales: Harada, Tomoyuki, Fink, Mitchell, Cruz, Ruy J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178866/
https://www.ncbi.nlm.nih.gov/pubmed/30365818
http://dx.doi.org/10.6061/clinics/2018/e332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178866/
https://www.ncbi.nlm.nih.gov/pubmed/30365818
http://dx.doi.org/10.6061/clinics/2018/e332

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