Early-life adversity selectively impairs α2-GABA(A) receptor expression in the mouse nucleus accumbens and influences the behavioral effects of cocaine

Haplotypes of the Gabra2 gene encoding the α2-subunit of the GABA(A) receptor (GABA(A)R) are associated with drug abuse, suggesting that α2-GABA(A)Rs may play an important role in the circuitry underlying drug misuse. The genetic association of Gabra2 haplotypes with cocaine addiction appears to be...

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Detalles Bibliográficos
Autores principales: Mitchell, Scott J., Maguire, Edward P., Cunningham, Linda, Gunn, Benjamin G., Linke, Matthias, Zechner, Ulrich, Dixon, Claire I., King, Sarah L., Stephens, David N., Swinny, Jerome D., Belelli, Delia, Lambert, Jeremy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178871/
https://www.ncbi.nlm.nih.gov/pubmed/30138693
http://dx.doi.org/10.1016/j.neuropharm.2018.08.021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178871/
https://www.ncbi.nlm.nih.gov/pubmed/30138693
http://dx.doi.org/10.1016/j.neuropharm.2018.08.021

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