Mahanimbine Exerts Anticancer Effects on Human Pancreatic Cancer Cells by Triggering Cell Cycle Arrest, Apoptosis, and Modulation of AKT/Mammalian Target of Rapamycin (mTOR) and Signal Transducer and Activator of Transcription 3 (STAT3) Signalling Pathways

BACKGROUND: Pancreatic cancer causes tremendous mortality across the globe mainly due to late diagnosis and unavailability of efficient chemotheruptic agents. In the current study the anticancer potential of a plant derived alkaloid, Mahanimbine, was examined against a panel of pancreatic cancer cel...

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Detalles Bibliográficos
Autores principales: Pei, Chenlin, He, Qun, Liang, Shuai, Gong, Xuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178883/
https://www.ncbi.nlm.nih.gov/pubmed/30273298
http://dx.doi.org/10.12659/MSM.911013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178883/
https://www.ncbi.nlm.nih.gov/pubmed/30273298
http://dx.doi.org/10.12659/MSM.911013

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