The ESCRT-III Protein CHMP1A Mediates Secretion of Sonic Hedgehog on a Distinctive Subtype of Extracellular Vesicles

Endosomal sorting complex required for transport (ESCRT) complex proteins regulate biogenesis and release of extracellular vesicles (EVs), which enable cell-to-cell communication in the nervous system essential for development and adult function. We recently showed human loss-of-function (LOF) mutat...

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Detalles Bibliográficos
Autores principales: Coulter, Michael E., Dorobantu, Cristina M., Lodewijk, Gerrald A., Delalande, François, Cianferani, Sarah, Ganesh, Vijay S., Smith, Richard S., Lim, Elaine T., Xu, C. Shan, Pang, Song, Wong, Eric T., Lidov, Hart G.W., Calicchio, Monica L., Yang, Edward, Gonzalez, Dilenny M., Schlaeger, Thorsten M., Mochida, Ganeshwaran H., Hess, Harald, Allen Lee, Wei-Chung, Lehtinen, Maria K., Kirchhausen, Tomas, Haussler, David, Jacobs, Frank M.J., Gaudin, Raphael, Walsh, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178983/
https://www.ncbi.nlm.nih.gov/pubmed/30044992
http://dx.doi.org/10.1016/j.celrep.2018.06.100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178983/
https://www.ncbi.nlm.nih.gov/pubmed/30044992
http://dx.doi.org/10.1016/j.celrep.2018.06.100

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