Cargando…

GSKJ4 Protects Mice Against Early Sepsis via Reducing Proinflammatory Factors and Up-Regulating MiR-146a

Sepsis, defined as life-threatening organ dysfunction, is one of the most common causes of mortality in intensive care units with limited therapeutic options. However, the mechanism underlying the regulation of epigenetics on sepsis remains largely undefined. Here we showed that JMJD3, the histone l...

Descripción completa

Detalles Bibliográficos
Autores principales: Pan, Yuchen, Wang, Jiali, Xue, Yaxian, Zhao, Jiaojiao, Li, Dan, Zhang, Shaolong, Li, Kuanyu, Hou, Yayi, Fan, Hongye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179039/
https://www.ncbi.nlm.nih.gov/pubmed/30337925
http://dx.doi.org/10.3389/fimmu.2018.02272