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GSKJ4 Protects Mice Against Early Sepsis via Reducing Proinflammatory Factors and Up-Regulating MiR-146a
Sepsis, defined as life-threatening organ dysfunction, is one of the most common causes of mortality in intensive care units with limited therapeutic options. However, the mechanism underlying the regulation of epigenetics on sepsis remains largely undefined. Here we showed that JMJD3, the histone l...
Autores principales: | Pan, Yuchen, Wang, Jiali, Xue, Yaxian, Zhao, Jiaojiao, Li, Dan, Zhang, Shaolong, Li, Kuanyu, Hou, Yayi, Fan, Hongye |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179039/ https://www.ncbi.nlm.nih.gov/pubmed/30337925 http://dx.doi.org/10.3389/fimmu.2018.02272 |
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