Design, synthesis, and biological evaluation of novel iso-flavones derivatives as H(3)R antagonists

Histamine H(3) receptor (H(3)R), a kind of G-protein coupled receptor (GPCR), is expressed mainly in the central nervous system (CNS) and plays a vital role in homoeostatic control. This study describes the design and synthesis of a series of novel H(3)R antagonists based on the iso-flavone scaffold...

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Detalles Bibliográficos
Autores principales: Xin, Jian, Hu, Min, Liu, Qian, Zhang, Tian Tai, Wang, Dong Mei, Wu, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179058/
https://www.ncbi.nlm.nih.gov/pubmed/30293461
http://dx.doi.org/10.1080/14756366.2018.1509212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179058/
https://www.ncbi.nlm.nih.gov/pubmed/30293461
http://dx.doi.org/10.1080/14756366.2018.1509212

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