Pharmacophore-based discovery of 2-(phenylamino)aceto-hydrazides as potent eosinophil peroxidase (EPO) inhibitors

There is an increasing interest in developing novel eosinophil peroxidase (EPO) inhibitors, in order to provide new treatment strategies against chronic inflammatory and neurodegenerative diseases caused by eosinophilic disorder. Within this study, a ligand-based pharmacophore model for EPO inhibito...

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Detalles Bibliográficos
Autores principales: Schuster, Daniela, Zederbauer, Martina, Langer, Thierry, Kubin, Andreas, Furtmüller, Paul G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179059/
https://www.ncbi.nlm.nih.gov/pubmed/30284485
http://dx.doi.org/10.1080/14756366.2018.1512598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179059/
https://www.ncbi.nlm.nih.gov/pubmed/30284485
http://dx.doi.org/10.1080/14756366.2018.1512598

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