ATF3 Deficiency Promotes Genome Instability and Spontaneous Tumorigenesis in Mice

Mice lacking genes involving in the DNA damage response (DDR) are often tumor prone owing to genome instability caused by oncogenic challenges. Previous studies demonstrate that activating transcription factor 3 (ATF3), a common stress sensor, can activate the tumor suppressor p53 and regulate expre...

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Detalles Bibliográficos
Autores principales: Wang, Ziyan, He, Yaqiong, Deng, Wuguo, Lang, Liwei, Yang, Heng, Jin, Bilian, Kolhe, Ravindra, Ding, Han-Fei, Zhang, Junran, Hai, Tsonwin, Yan, Chunhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179156/
https://www.ncbi.nlm.nih.gov/pubmed/28869597
http://dx.doi.org/10.1038/onc.2017.310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179156/
https://www.ncbi.nlm.nih.gov/pubmed/28869597
http://dx.doi.org/10.1038/onc.2017.310

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