Cargando…

Apolipoprotein E is a pancreatic extracellular factor that maintains mature β-cell gene expression

The in vivo microenvironment of tissues provides myriad unique signals to cells. Thus, following isolation, many cell types change in culture, often preserving some but not all of their in vivo characteristics in culture. At least some of the in vivo microenvironment may be mimicked by providing spe...

Descripción completa

Detalles Bibliográficos
Autores principales: Mahmoud, Ahmed I., Galdos, Francisco X., Dinan, Katherine A., Jedrychowski, Mark P., Davis, Jeffrey C., Vujic, Ana, Rachmin, Inbal, Shigley, Christian, Pancoast, James R., Lee, Samuel, Hollister-Lock, Jennifer, MacGillivray, Catherine M., Gygi, Steven P., Melton, Douglas A., Weir, Gordon C., Lee, Richard T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179231/
https://www.ncbi.nlm.nih.gov/pubmed/30303984
http://dx.doi.org/10.1371/journal.pone.0204595