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Apolipoprotein E is a pancreatic extracellular factor that maintains mature β-cell gene expression
The in vivo microenvironment of tissues provides myriad unique signals to cells. Thus, following isolation, many cell types change in culture, often preserving some but not all of their in vivo characteristics in culture. At least some of the in vivo microenvironment may be mimicked by providing spe...
Autores principales: | Mahmoud, Ahmed I., Galdos, Francisco X., Dinan, Katherine A., Jedrychowski, Mark P., Davis, Jeffrey C., Vujic, Ana, Rachmin, Inbal, Shigley, Christian, Pancoast, James R., Lee, Samuel, Hollister-Lock, Jennifer, MacGillivray, Catherine M., Gygi, Steven P., Melton, Douglas A., Weir, Gordon C., Lee, Richard T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179231/ https://www.ncbi.nlm.nih.gov/pubmed/30303984 http://dx.doi.org/10.1371/journal.pone.0204595 |
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